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Product Name human CD59/PE Chinese Name PE标记人CD59单克隆抗体 Alias CD59 glycoprotein; CD59 molecule (CD59 blood group); 1F5 antigen; 20 kDa homologous restriction factor; MAC-inhibitory protein; Membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MEM43 antigen; MACIF; 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20; CD59_HUMAN. Immunogen Species Mouse Clonality Monoclonal Clone NO. 8A1 React Species (predicted: Human, ) Applications Flow-Cyt=10ul/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 9kDa Detection molecular weight 19-25 Form Liquid Lsotype Mouse IgG1, k Purification Affinity purified by Protein G Buffer Solution 0.01M PBS, 0.5%BSA, 0.03% Proclin300 Storage Store at 2-8℃. Protect from light. Avoid freezing. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
SWISS:
P13987
Gene ID:
966
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