Product Name	human CD45RB/PE
Chinese Name	PE标记人CD45RB单克隆抗体
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	45F2
React Species	(predicted: Human, )
Applications	Flow-Cyt=10ul/Test  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Detection molecular weight	220
Form	Liquid
Lsotype	Mouse IgG2b, κ
Purification	Affinity purified by Protein G
Buffer Solution	0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage	Store at 2-8℃. Protect from light. Avoid freezing.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naïve T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naïve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1. SWISS: P08575 Gene ID: 5788

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