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Product Name HBsAg, Alexa Fluor 750 conjugated Chinese Name AF750标记的山羊抗人乙肝表面抗原抗体 Alias L glycoprotein; L-HBsAg; LHB; Large S protein; Large surface protein; Major surface antigen; S; HBSAG_HBVC5. Research Area Microbiology Bacteria and viruses Immunogen Species Goat Clonality Polyclonal React Species (predicted: Human, ) Applications IF=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 44kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen Recombinant HBsAg protein Lsotype IgG Purification affinity purified by Protein G Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
SWISS:
P03140
Gene ID:
944569
Database links:Entrez Gene: 2828293 Hepatitis B virus
Entrez Gene: 944569 Hepatitis B virus
SwissProt: P03138 Hepatitis B virus
SwissProt: P03140 Hepatitis B virus
SwissProt: P03141 Hepatitis B virus
SwissProt: Q81157 Hepatitis B virus
SwissProt: Q81158 Hepatitis B virus
SwissProt: Q81159 Hepatitis B virus
SwissProt: Q81160 Hepatitis B virus
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