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Rabbit Anti-GPR30 , Alexa Fluor 750 conjugated antibody
Rabbit Anti-GPR30 , Alexa Fluor 750 conjugated antibody
G Protein Coupled Receptor 30; G-protein coupled receptor 30; G-protein coupled estrogen receptor 1; Membrane estrogen receptor; mER; Chemokine receptor-like 2; IL8-related receptor DRY12; Flow-induced endothelial G-protein coupled receptor 1; FEG-1; Lymp
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  • NO.:SL20642R-AF750
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,)
    Applications:IF
    concentration:1mg/ml
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Details

Product Name GPR30, Alexa Fluor 750 conjugated
Chinese Name AF750标记的G protein-coupled receptor30抗体
Alias G Protein Coupled Receptor 30; G-protein coupled receptor 30; G-protein coupled estrogen receptor 1; Membrane estrogen receptor; mER; Chemokine receptor-like 2; IL8-related receptor DRY12; Flow-induced endothelial G-protein coupled receptor 1; FEG-1; Lymphocyte-derived G-protein coupled receptor; LYGPR; GPCR-BR; CEPR; CMKRL2; DRY12; GPER.  
Research Area Cell biology  Neurobiology  Signal transduction  The cell membrane受体  G protein-coupled receptor  G protein signal  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, )
Applications IF=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 42kDa
Cellular localization The nucleus cytoplasmic The cell membrane Extracellular matrix 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GPR30: 21-120/375 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail G protein-coupled receptors (GPRs, or GPCRs) contain 7 hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops and transduce a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins. GRP30 is a member of this family and is an orphan receptor. GPR30 expression has been reported in brain, breast carcinoma, blood, bone marrow, CNS, heart, liver, lung, lymph node, placenta, and spleen. In brain, GPR30 is expressed as a 2.8 kb transcript in basal forebrain, frontal cortex, thalamus, hippocampus, caudate and putamen. However, unlike other known G protein-coupled receptors, GPR30 localizes to the endoplasmic reticulum, where it specifically binds estrogen and estrogen derivatives.

SWISS:
Q99527

Gene ID:
2852

Database links:

Entrez Gene: 2852 Human

Entrez Gene: 76854 Mouse

Entrez Gene: 171104 Rat

Omim: 601805 Human

SwissProt: Q99527 Human

SwissProt: Q8BMP4 Mouse

SwissProt: O08878 Rat

Unigene: 20961 Human

Unigene: 389706 Mouse

Unigene: 9806 Rat



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