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Product Name MDFI, Alexa Fluor 750 conjugated Chinese Name AF750标记的抑制肌原调节蛋白1抗体 Alias I MF; I mfa; Inhibitor of MyoD family a; Mdfi; MDFI_HUMAN; MyoD family inhibitor; Myogenic repressor I-mf; OTTHUMP00000016375; OTTHUMP00000016376; OTTHUMP00000196103; OTTHUMP00000196414; OTTHUMP00000196415. Research Area Cell biology Developmental biology transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, ) Applications IF=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 25kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MDFI: 101-200/246 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq, Jul 2008]
SWISS:
Q99750
Gene ID:
4188
Database links:Entrez Gene: 4188 Human
Entrez Gene: 17240 Mouse
Omim: 604971 Human
SwissProt: Q99750 Human
SwissProt: P70331 Mouse
Unigene: 520119 Human
Unigene: 329100 Mouse
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