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Product Name Collagen I, Alexa Fluor 750 conjugated Chinese Name AF750标记的I型胶原单克隆抗体 Alias Collagen type I; Alpha 1 type I collagen; Alpha 2 type I collagen; COL1A1; COL1A2; Collagen I alpha 1 polypeptide; Collagen I alpha 2 polypeptide; Collagen Of Skin Tendon And Bone; Collagen Type 1; Collagen type I alpha 1; Collagen type I alpha 2; OI4; Osteogenesis Imperfecta Type IV; Pro alpha 1(I) collagen; Type I procollagen; CO1A1_HUMAN; Collagen alpha-1(II) chain; Alpha-1 type II collagen; Collagen alpha-1(II) chain; Chondrocalcin; collagen alpha-1(I) chain preproprotein. Research Area Cell biology immunology Extracellular matrix Immunogen Species Mouse Clonality Monoclonal Clone NO. 7C7 React Species (predicted: Human, Mouse, Rat, ) Applications IF=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 139kDa Cellular localization Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Collagen I Lsotype IgG Purification affinity purified by Protein G Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008].
SWISS:
P02452
Gene ID:
1277
Database links:
Entrez Gene: 1277 Human
Entrez Gene: 1278 Human
Entrez Gene: 12842 Mouse
Entrez Gene: 12843 Mouse
Omim: 120150 Human
Omim: 120160 Human
SwissProt: P02452 Human
SwissProt: P08123 Human
SwissProt: P11087 Mouse
SwissProt: Q01149 Mouse
Unigene: 172928 Human
Unigene: 489142 Human
Unigene: 681002 Human
Unigene: 277735 Mouse
Unigene: 458212 Mouse
Unigene: 107239 Rat
Unigene: 2953 Rat
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