Product Name	beta-Amyloid (1-42)
Chinese Name	β淀粉样肽（1-42）单克隆抗体
Alias	beta-Amyloid(1-42); A4; AAA; ABETA; ABPP; AD1; Alzheimers Disease Amyloid Protein; Amyloid B; Amyloid Beta A4 Protein Precursor; Amyloid Beta; Amyloid of Aging and Alzheimer Disease; APP; APPI; B Amyloid; Beta APP; Cerebral Vascular Amyloid Peptide; CTFgamma; CVAP; PN II; PN2; PreA4; Protease nexin II; A beta; Amyloid 1-42.
Research Area	Cell biology  immunology  Neurobiology  Alzheimer's
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	1F9
React Species	(predicted: Human, )
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	4.4kDa
Cellular localization	The nucleus cytoplasmic The cell membrane Extracellular matrix
Form	Liquid
immunogen	KLH conjugated synthetic peptide derived from human beta-Amyloid (1-42) : 1-42/42 <Cytoplasmic>
Lsotype	IgG2a
Purification	affinity purified by Protein A
Buffer Solution	0.01M PBS(pH7.4)
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease. SWISS: P05067 Gene ID: 351 Database links: Entrez Gene: 351 Human Entrez Gene: 11820 Mouse Entrez Gene: 54226 Rat Omim: 104760 Human SwissProt: P05067 Human SwissProt: P12023 Mouse SwissProt: P08592 Rat Unigene: 434980 Human Unigene: 277585 Mouse Unigene: 2104 Rat

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