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Product Name Creatine Kinase MB (CK-MB) Chinese Name 肌酸激酶同工酶MB单克隆抗体 Research Area Cardiovascular Immunogen Species Mouse Clonality Monoclonal Clone NO. 7C9 Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Cellular localization cytoplasmic Form Liquid Concentration ≥0.6 mg/ml immunogen Recombinant human Creatine Kinase MB (CK-MB) Lsotype IgG1 Buffer Solution potassium phosphate buffer and sodium chloride. No preservatives are added Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]
Function:
Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa.
Subcellular Location:
Cytoplasmic and Mitochondrial
Similarity:
Belongs to the ATP:guanido phosphotransferase family.
Contains 1 phosphagen kinase C-terminal domain.
Contains 1 phosphagen kinase N-terminal domain.
SWISS:
P06732
Gene ID:
1152
Database links:Entrez Gene: 1152 Human
Entrez Gene: 1158 Human
Omim: 123310 Human
SwissProt: P06732 Human
SwissProt: P12277 Human
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