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Product Name Nucleophosmin Chinese Name Immunogen Species Mouse Clonality Monoclonal Clone NO. H7C2 React Species (predicted: Human, ) Applications WB=1:500-1:1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Cellular localization The nucleus The cell membrane Form Liquid Concentration 1mg/ml Lsotype IgG1/Kappa Purification Affinity purified by Protein G Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail 参与多种细胞过程,如核糖体生物发生、中心体复制、蛋白质伴侣、组蛋白组装、细胞增殖和Tumour抑制因子p53/TP53和ARF的调控。结合核糖体可能驱动核糖体核输出。与核仁核糖核蛋白结构相关并结合单链核酸。作为核心组蛋白H3、H2B和H4的伴侣蛋白。刺激无嘌呤/无嘧啶(AP)双链DNA上的APEX1内切酶活性,但抑制AP单链RNA上的APEX1内切酶活性。可能对核仁内的APEX1内切酶活性施加控制,用于修复rDNA上的AP和去除氧化的rRNA分子。与BRCA2共同调节中心体复制。 Product Picture
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