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Product Name CD2 Chinese Name CD2Recombinant rabbit monoclonal anti Alias CD2_HUMAN; T-cell surface antigen CD2; T cell surface antigen CD2; SRBC; Erythrocyte receptor; LFA-2; LFA2; LFA3 receptor; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD 2; CD2 antigen; CD2 molecule; Research Area Cell biology immunology Stem cells Cell Surface Molecule glycoprotein Natural killer cells lymphocyte t-lymphocyte b-lymphocyte Immunogen Species Rabbit Clonality Monoclonal Clone NO. C11G5 React Species Human, Applications IP=1:200-1000 ICC=1:50 IF=1:50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 37kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CD2 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016]
Function:
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Subunit:
Interacts with CD2AP. Interacts with PSTPIP1.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
SWISS:
P06729
Gene ID:
914
Database links:Entrez Gene: 914 Human
Entrez Gene: 12481 Mouse
Omim: 186990 Human
SwissProt: P06729 Human
SwissProt: P08920 Mouse
Unigene: 523500 Human
Unigene: 22842 Mouse
Unigene: 10328 Rat
Product Picture Tissue:Human colon
Section type: Formalin fixed & Paraffin -embedded section
Retrieval method: High temperature and high pressure
Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:1000
Primary ab incubation condition: 1 hour at room temperature
Counter stain: Hematoxylin
Comment: Color brown is the positive signal for SLM-60313R
Tissue:Human tonsil
Section type: Formalin fixed & Paraffin -embedded section
Retrieval method: High temperature and high pressure
Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:1000
Primary ab incubation condition: 1 hour at room temperature
Counter stain: Hematoxylin
Comment: Color brown is the positive signal for SLM-60313R
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