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Product Name Thymidylate Synthase Chinese Name Immunogen Species Rabbit Clonality Monoclonal Clone NO. G1E8 React Species (predicted: Human, ) Applications WB=1:500-1:1000 IHC-P=1:100-500 ICC=1:50 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Cellular localization The nucleus cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml Lsotype IgG Purification Affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail 胸腺嘧啶核苷酸合酶(TS)是合成2'-脱氧核糖核酸-5'-单磷酸盐的关键酶,是DNA生物合成的重要前体。由于胸腺嘧啶核苷酸合酶是Mitochondrion胸腺嘧啶从头合成途径的关键酶,因此这种酶是癌症化疗的关键靶点。它被认为是5-氟尿酸、5-氟-2’-脱氧核糖核酸和一些叶酸类化合物的主要作用靶点。
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