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Product Name MAGEA1 Chinese Name Immunogen Species Rabbit Clonality Monoclonal Clone NO. B11C9 React Species (predicted: Human, ) Applications WB=1: 500-1: 2000 IHC-P=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Cellular localization The nucleus The cell membrane Form Liquid Concentration 1mg/ml Lsotype IgG Purification Affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail 人恶性Tumour携带排斥抗原,这些抗原可被患者的自体、Tumour定向和特异性、细胞溶解性、CD8+ Tlymphocyte克隆(CTL)识别。一个重要的抗原组由MAGE家族的基因编码。因为MAGE-1在人类各种Tumour组织(黑色素瘤、脑的神经胶质Tumour起源、神经母细胞瘤、非小细胞肺癌,乳腺癌、胃癌、直肠癌、卵巢癌,肾细胞癌)有重要表达,而正常组织没有,所以可作为早期诊断的一个标志和治疗靶标。
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