Product Name	KDM5C
Chinese Name
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	H4A2
React Species	(predicted: Human, )
Applications	WB=1:1000 ICC=1:50  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG1/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	组蛋白去甲基化酶，特异性地去甲基化组蛋白H3的‘Lys-4’，从而在组蛋白编码中起中心作用。不去甲基化组蛋白H3'Lys-9'，H3'Lys-27'，H3'Lys-36'，H3'Lys-79'或H4'Lys-20'。脱甲基三甲基化和二甲基化但不单甲基化的H3‘Lys-4’。通过招募组蛋白去乙酰化酶参与神经元基因的转录抑制，并在神经元限制性沉默元件处休息。抑制CLOCK-ARNTL/BMAL1异二聚体介导的核心时钟成分PER2的转录激活

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