Product Name	CECR2
Chinese Name
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	G4E5
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:1000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG1/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	组蛋白修饰复合物的染色质读取器组分，如CERF（含重构因子的CECR2）复合物和ISWI型复合物。因此，它在发育过程中的各种过程中发挥作用。在胚胎发生过程中，神经管闭合和内耳发育都需要它。在成人中，通过形成ISWI型染色质复合体来实现精子发生。在组蛋白修饰复合物中，CECR2识别并结合酰化组蛋白，结合乙酰化和/或丁基酰化的组蛋白。也可能通过其与lrprc的相互作用参与Cytoskeleton网络与囊泡运输、核浆穿梭、转录、染色体重构和胞质分裂的整合。
Product Picture	Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:1000 Primary ab incubation condition: 2 hours at room temperature Lysate: HeLa, HepG2, N2a, EL4.IL-2, BRL Protein loading quantity: 20 μg Exposure time: 30 s Predicted MW: 58 kDa Observed MW: 58 kDa

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