Product Name	CD43
Chinese Name	CD43Recombinant rabbit monoclonal anti
Alias	LEUK_HUMAN; Leukosialin; SPN; GPL115; GALGP; GPL 115; Galactoglycoprotein (GALGP); Leukocyte sialoglycoprotein; Sialophorin; CD43 cytoplasmic tail; CD 43; CD43 antigen;
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	H6G11
React Species	(predicted: Human, )
Applications	WB=1:10000-20000 Flow-Cyt=1:100  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	38kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	0.5mg/ml
Lsotype	IgG
Purification	Affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017] Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas. SWISS: P16150 Gene ID: 6693 Database links: Entrez Gene: 6693 Human Entrez Gene: 20737 Mouse SwissProt: P16150 Human SwissProt: P15702 Mouse CD43又名白细胞唾液酸glycoprotein或唾液酸蛋白，是一种跨膜表面蛋白，在人体中有SPN（唾液蛋白）基因编码。CD43分子中的缺陷与Wiskott-Aldrich综合征的发病有关。
Product Picture	Sample: Lane 1: Human U937 cell lysates Lane 2: Human K562 cell lysates Lane 3: Human Jurkat cell lysates Primary: Anti-CD43 (SLM-60237R) at 1/10000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kDa Observed band size: 105 kDa

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