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Product Name Galectin 8 Chinese Name 半乳糖凝集素8Recombinant rabbit monoclonal anti Alias Gal 8; Gal-8; Gal8; Galectin-8; LEG8_HUMAN; LGAL S8; LGALS8; PCTA 1; PCTA-1; PCTA1; Po66 carbohydrate binding protein; Po66 carbohydrate-binding protein; Po66 CBP; Po66-CBP; Prostate carcinoma tumor antigen 1. Research Area Tumour immunology Cell adhesion molecule Immunogen Species Rabbit Clonality Monoclonal Clone NO. 1A4 React Species Human, (predicted: Mouse, Rat, ) Applications WB=1:500-1000 IP=1:20-100 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:400-800 IF=1:400-800 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 35kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Galectin 8 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Ubiquitous. Selective expression by prostate carcinomas versus normal prostate and benign prostatic hypertrophy.
Similarity:
Contains 2 galectin domains.
SWISS:
O00214
Gene ID:
3964
Database links:Entrez Gene: 3964 Human
Entrez Gene: 56048 Mouse
Omim: 606099 Human
SwissProt: O00214 Human
SwissProt: Q9JL15 Mouse
Unigene: 4082 Human
Unigene: 708114 Human
Unigene: 448495 Mouse
Unigene: 474138 Mouse
Unigene: 10069 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by microwaving in EDTA buffer (Ph8.0) for 5min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Galectin 8) Monoclonal Antibody, Unconjugated (SLM-54301R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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