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Mouse Anti-Adenylate Kinase 1 antibody
Mouse Anti-Adenylate Kinase 1 antibody
AK 1; AK1; AK-1; KAD1_HUMAN; Adenylate kinase isoenzyme 1; Adenylate kinase soluble; ATP AMP transphosphorylase; Myokinase; ATP-AMP transphosphorylase 1.
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  • NO.:SLM-51669M
    Clonality:Monoclonal
    Immunogen Species:Mouse
    React Species:Human,
    Applications:WB IHC-P
    concentration:1mg/ml
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Product Name Adenylate Kinase 1
Chinese Name 腺苷酸激酶-1单克隆抗体
Alias AK 1; AK1; AK-1; KAD1_HUMAN; Adenylate kinase isoenzyme 1; Adenylate kinase soluble; ATP AMP transphosphorylase; Myokinase; ATP-AMP transphosphorylase 1.  
Research Area Tumour  Cardiovascular  Signal transduction  The new supersedes the old  
Immunogen Species Mouse
Clonality Monoclonal
Clone NO. G6E1
React Species Human, 
Applications WB=1:500-4000 IHC-P=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 21kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen Recombinant human AK1 between 1-193 amino acids. 
Lsotype IgG1,k
Purification affinity purified by Protein G
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Function:
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth.

Subunit:
Monomer.

Subcellular Location:
Cytoplasm.

DISEASE:
Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency (HAAKD) [MIM:612631].

Similarity:
Belongs to the adenylate kinase family.

SWISS:
P00568

Gene ID:
203

Database links:

Entrez Gene: 203 Human

SwissProt: P00568 Human



Product Picture
Sample:
Lane 1: 293 cell lysates
Lane 2: HepG2 cell lysates
Lane 3: Human testis tissue lysates
Primary: Anti-Adenylate Kinase 1 (SLM-51669M) at 1/4000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 21 kD
Observed band size: 24 kD

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