TEL: +86 571 56623320 EMAIL: [email protected]
Product Name REG3G Chinese Name REG3G单克隆抗体 Alias Reg III gamma; REG3G_HUMAN; Reg3 gamma; Reg3gamma; Reg-3gamma; Regenerating islet-derived protein 3-gamma; REG-3-gamma; Pancreatitis-associated protein 1B; PAP-1B; Pancreatitis-associated protein IB; PAP IB; Regenerating islet-derived protein III-gamma; Reg III-gamma. Research Area immunology Immunogen Species Mouse Clonality Monoclonal Clone NO. F6D9 React Species Human, Applications WB=1:500-1000 IHC-P=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 17kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen Recombinant human REG3G. Lsotype IgG1,k Purification affinity purified by Protein G Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The regeneration (REG) family consists of secretory proteins involved in liver, pancreatic, gastric and intestinal cell proliferation or differentiation. Members of the REG family are divided into four subclasses, designated types I, II, III and IV, all of which share a common gene structure containing five introns and six exons. Members of the Reg family have been implicated in the regulation of cell growth, tumorigenesis and the progression of cancer. Reg lll(regenerating islet-derived 3 gamma), also known as pancreatitis-associated protein 1B, PAP1B, or UNQ429, is a 175 amino acid secreted protein that is expressed almost exclusively in pancreas, with low levels of expression in testis. Reg lll?functions as an antimicrobial protein involved in controlling bacterial proliferation and may be induced during acute pancreatitis. The gene encoding Reg lll?maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome.
Function:
Might be a stress protein involved in the control of bacterial proliferation.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed almost exclusively in the pancreas. Also expressed in testis. Not found in small intestine.
Similarity:
Contains 1 C-type lectin domain.
SWISS:
Q6UW15
Gene ID:
130120
Database links:
Entrez Gene: 130120 HumanSwissProt: Q6UW15 Human
Product Picture Sample:
Lane 1: Human Pancreas tissue lysates
Primary: Anti-REG3G (SLM-51653M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 17 kD
Observed band size: 17 kD
Paraformaldehyde-fixed, paraffin embedded (human pancreas tissue sections); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (REG3G) Monoclonal Antibody, Unconjugated (SLM-51653M) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Mouse)(sp-0024) instructionsand DAB staining.
Scan Wechat Qrcode
Scan Whatsapp Qrcode