Product Name	PACSIN2
Chinese Name	胞浆磷蛋白PACSIN2单克隆抗体
Alias	cytoplasmic phosphoprotein PACSIN2; Moderately similar to h74 gene product; OTTHUMP00000198281; OTTHUMP00000198282; OTTHUMP00000198283; OTTHUMP00000198284; PACN2_HUMAN; protein kinase C and casein kinase substrate in neurons 2; protein kinase C and casein kinase substrate in neurons 2; Protein kinase C and casein kinase substrate in neurons protein 2; Protein kinase C and casein kinase substrate in neurons protein; SDP II; SDPII; Syndapin II.
Research Area	Cell biology  Neurobiology  Signal transduction
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	H5F12
React Species	Human,  (predicted: Mouse, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	56kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	Recombinant human PACSIN2 between 250-486 amino acids.
Lsotype	IgG1,k
Purification	affinity purified by Protein G
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] Function: May play a role in vesicle formation and transport. Subunit: Homodimer. May form heterooligomers with other PACSINs.Interacts (via NPF motifs) with EHD1 (via EH domain). Interacts with EHD3. Interacts (via the SH3 domain) with MICALL1. Interacts with RAC1. Interacts (via SH3 domain) with DNM1, SYN1, SYNJ1 and WASL. Interacts with CAV1. Interacts with TRPV4. Subcellular Location: Cytoplasmic vesicle. Vesicle-like cytoplasmic distribution. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). Similarity: Belongs to the PACSIN family. Contains 1 FCH domain. Contains 1 SH3 domain. SWISS: Q9UNF0 Gene ID: 11252 Database links: Entrez Gene: 11252 Human Entrez Gene: 23970 Mouse SwissProt: Q9UNF0 Human SwissProt: Q9WVE8 Mouse
Product Picture	Sample: Lane 1: Daudi cell lysates Lane 2: PC-3 cell lysates Lane 3: Human brain tissue lysates Lane 4: Mouse brain tissue lysates Primary: Anti-PACSIN2 (SLM-51639M) at 1/2000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 58 kD

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