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Mouse Anti-MYB antibody
Mouse Anti-MYB antibody
Avian myeloblastosis viral (v-myb) oncogene homolog; C myb; c-Myb; MYB_HUMAN; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog.
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Details

Product Name MYB
Chinese Name 转录激活因子MYB单克隆抗体
Alias Avian myeloblastosis viral (v-myb) oncogene homolog; C myb; c-Myb; MYB_HUMAN; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog.  
Research Area Tumour  immunology  Chromatin and nuclear signals  transcriptional regulatory factor  Epigenetics  
Immunogen Species Mouse
Clonality Monoclonal
Clone NO. F33A1
React Species Human, 
Applications WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 84kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human MYB: 31-150/640 
Lsotype IgG1,κ
Purification affinity purified by Protein G
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Function:
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Subcellular Location:
Nucleus.

Post-translational modifications:
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.
Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.

Similarity:
Contains 3 HTH myb-type DNA-binding domains.

SWISS:
P10242

Gene ID:
4602

Database links:

Entrez Gene: 4602 Human

SwissProt: P10242 Human



Product Picture
Sample:
Lane 1: Jurkat cell lysates
Lane 2: CCRF-CEM cell lysates
Primary: Anti-MYB (SLM-51579M) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 84 kD
Observed band size: 84 kD

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