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Product Name MYB Chinese Name 转录激活因子MYB单克隆抗体 Alias Avian myeloblastosis viral (v-myb) oncogene homolog; C myb; c-Myb; MYB_HUMAN; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog. Research Area Tumour immunology Chromatin and nuclear signals transcriptional regulatory factor Epigenetics Immunogen Species Mouse Clonality Monoclonal Clone NO. F33A1 React Species Human, Applications WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 84kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MYB: 31-150/640 Lsotype IgG1,κ Purification affinity purified by Protein G Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Function:
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Subcellular Location:
Nucleus.
Post-translational modifications:
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.
Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.
Similarity:
Contains 3 HTH myb-type DNA-binding domains.
SWISS:
P10242
Gene ID:
4602
Database links:Entrez Gene: 4602 Human
SwissProt: P10242 Human
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