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Product Name PRDM10 Chinese Name PRDM10k单克隆抗体 Alias PR domain zinc finger protein 10; PRD10_HUMAN; PR domain zinc finger protein 10; PR domain-containing protein 10; Tristanin. Research Area Tumour Cell biology transcriptional regulatory factor Cell differentiation b-lymphocyte Zinc finger protein Epigenetics Immunogen Species Mouse Clonality Monoclonal Clone NO. B10F7 React Species Human, (predicted: Mouse, ) Applications WB=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 130kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen Recombinant GST fusion protein encoding the N-terminal part of human PRDM10 Lsotype IgG1 Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Function:
May be involved in transcriptional regulation.
Subcellular Location:
Nucleus.
Similarity:
Contains 10 C2H2-type zinc fingers.
Contains 1 SET domain.
SWISS:
Q9NQV6
Gene ID:
56980
Database links:Entrez Gene: 56980 Human
Entrez Gene: 382066 Mouse
SwissProt: Q9NQV6 Human
SwissProt: Q3UTQ7 Mouse
Unigene: 275086 Human
Unigene: 335039 Mouse
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