Product Name	FABP4
Chinese Name	脂肪细胞型脂肪酸Binding protein单克隆抗体
Alias	adipocyte; 3T3-L1 lipid-binding protein; 422/aP2; A FABP; A-FABP; Adipocyte lipid binding protein; Adipocyte lipid-binding protein; Adipocyte protein AP2; Adipocyte-type fatty acid-binding protein; AFABP; ALBPv ALBP/Ap2; aP2; FABP; FABP4_HUMAN; Fatty acid binding protein 4 adipocyte; Fatty acid binding protein 4; Fatty acid binding protein adipocyte; Fatty acid-binding protein 4; Fatty acid-binding protein; Lbpl; Myelin P2 protein homolog; P15v P2 adipocyte protein; Protein 422.
literatures	Specific References  (5)     |     SLM-51247M has been referenced in 5 publications. [IF=7.012] Mengqi Su. et al. Epididymal white adipose tissue promotes angiotensin II-induced cardiac fibrosis in an exosome-dependent manner. TRANSL RES. 2022 May;:  FC ;  Mouse.   PubMed:35609783 [IF=5.923] Yonglin Hua. et al. Ablation of KDM2A Inhibits Preadipocyte Proliferation and Promotes Adipogenic Differentiation. Int J Mol Sci. 2021 Jan;22(18):9759  IF ;  Mouse.   PubMed:34575926 [IF=5.201] Xuemei Shen. et al. CircINSR Regulates Fetal Bovine Muscle and Fat Development. Front Cell Dev Biol. 2020; 8: 615638  WB ;  Bovine.   PubMed:33490079 [IF=4.861] Xuemei Shen. et al. CircRNF111 Contributes to Adipocyte Differentiation by Elevating PPARγ Expression via miR-27a-3p. EPIGENETICS-US. 2022 Nov 15  WB ;  Bovine.   PubMed:36377797 [IF=1.966] Zhang Y et al. High expression of FABP4 and FABP6 in patients with colorectal cancer. World J Surg Oncol. 2019 Oct 24;17(1):171.  IHC-P&WB ;  Human.   PubMed:31651326
Research Area	Tumour  immunology  transcriptional regulatory factor
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	6F3
React Species	Mouse,  (predicted: Human, )
Applications	WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:20-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	14kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	Recombinant human FABP4 protein
Lsotype	IgG1
Purification	affinity purified by Protein G
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq]. Function: Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. Subunit: Monomer. Homodimer. Interacts with PPARG. Subcellular Location: Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export. Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. SWISS: P15090 Gene ID: 2167 Database links: Entrez Gene: 2167 Human Entrez Gene: 11770 Mouse Entrez Gene: 79451 Rat Omim: 600434 Human SwissProt: P15090 Human SwissProt: P04117 Mouse SwissProt: P70623 Rat Unigene: 391561 Human Unigene: 582 Mouse Unigene: 4258 Rat
Product Picture	Sample: Lane 1: Mouse Adipose tissue lysates Lane 2: Mouse Breast tissue lysates Lane 3: Mouse Heart tissue lysates Lane 4: Mouse Thymus tissue lysates Primary: Anti-FABP4 (SLM-51247M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 14 kDa

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