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Mouse Anti-Myoglobin antibody
Mouse Anti-Myoglobin antibody
MB; MGC13548; Myoglobin; PVALB; MYG_HUMAN.
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Details

Product Name Myoglobin
Chinese Name 肌红蛋白单克隆抗体
Alias MB; MGC13548; Myoglobin; PVALB; MYG_HUMAN.  
Research Area Tumour  Cell biology  immunology  
Immunogen Species Mouse
Clonality Monoclonal
Clone NO. 3A9
React Species (predicted: Human, Mouse, )
Applications WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 17kDa
Cellular localization cytoplasmic Secretory protein 
Form Liquid
Concentration 1mg/1ml
immunogen KLH conjugated synthetic peptide derived from human Myoglobin 
Lsotype IgG1
Purification affinity purified by Protein G
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.

Function:
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Subcellular Location:
Cytosol; Extracellular region or secreted

Similarity:
Belongs to the globin family.

SWISS:
P02144

Gene ID:
4151

Database links:

Entrez Gene: 4151 Human

Entrez Gene: 17189 Mouse

Entrez Gene: 59108 Rat

Omim: 160000 Human

SwissProt: P02144 Human

SwissProt: P04247 Mouse

SwissProt: Q9QZ76 Rat

Unigene: 517586 Human

Unigene: 404074 Mouse

Unigene: 40511 Rat



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