TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Human Ig Kappa light chain Chinese Name 人k轻链单克隆抗体 Alias Kappa Light Chain; IGKC; HCAK 1; HCAK1; Ig kappa chain C region; IGKC; Immunoglobulin kappa constant; Immunoglobulin kappa constant region; Immunoglobulin kappa light chain; Kappa 1 immunoglobulin light chain; Km; MGC111575; MGC62011; MGC72072; MGC88770; MGC88771; MGC88809; Human Ig/L-Chain Kappa; IGKC_HUMAN. Research Area Cell biology immunology Immunogen Species Mouse Clonality Monoclonal Clone NO. 6H8 React Species Human, Applications WB=1:100-1000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:20-200 ICC=1:20-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 11kDa Cellular localization The cell membrane Secretory protein Form Liquid Concentration 1mg/ml immunogen Recombinant human Kappa light chain Lsotype IgG1 Purification affinity purified by Protein G Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers.
Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
SWISS:
P01834
Gene ID:
3514
Database links:
Entrez Gene: 3514 Human
Omim: 147200 Human
SwissProt: P01834 Human
Unigene: 449609 Human
Product Picture
Scan Wechat Qrcode