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Product Name SARS-CoV Nucleocapsid Chinese Name SARS病毒核衣壳蛋白单克隆抗体 Alias N [SARS coronavirus ShanghaiQXC2]; literatures Specific References (1) | SLM-49131M has been referenced in 1 publications.[IF=1.902] Shambhunath Choudhary. et al. Modeling SARS-CoV-2: Comparative Pathology in Rhesus Macaque and Golden Syrian Hamster Models:. Toxicol Pathol. 0;(): IHC ; Monkey(Macaque),Hamster.Research Area Bacteria and viruses Immunogen Species Mouse Clonality Monoclonal Clone NO. 8G8A Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 46kDa Form Liquid Concentration ≥1mg/ml immunogen Recombinant SARS N (nucleocapsid) : 1-422/422aa Lsotype IgG2b Purification affinity purified by Protein G Buffer Solution 0.01M PBS(pH7.4) with 0.1% Proclin300 Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The nucleocapsid (N) protein of SARS-coronavirus (SARS-CoV) is the key protein for the formation of the helical nucleocapsid during virion assembly. The nucleocapsid (N) protein of SARS-CoV enters the host cell together with the viral RNA and interferes with several cellular processes. Some of these processes involve interactions between SARS-CoV N protein and host-cell proteins. It has also been demonstrated that the SARS-CoV N protein can bind to DNA in vitro. These interactions might have a role in the pathology of SARS. The N protein may be of potential value in vaccine development for specific prophylaxis and treatment against SARS.
SWISS:
N/A
Gene ID:
N/A
Product Picture Sample:
Lane 1: 2019-nCoV Nucleocapsid Protein full length (His tag) Overexpression E.coli Lysate (Cat#: SL41408P) at 30 ug
Lane 2: Recombinant SARS N (1-422) protein (Cat#: SL49002P) at 5 ug
Primary: Anti-SARS N (nucleocapsid) (SLM-49131M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
Sample:
Lane 1: SARS-CoV-2 N Protein (Cat#: NP) at 4 ug
Lane 2: Recombinant SARS N (1-422) protein (Cat#: SL49002P) at 5 ug
Lane 3: MERS N protein (Cat#: SL40068-V08B) at 2 ug
Primary: Anti-SARS N (nucleocapsid) (SLM-49131M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
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