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Product Name SARS-CoV-2 (2019-nCoV) Nucleocapsid Chinese Name SARS冠状病毒2核衣壳蛋白单克隆抗体 Alias SARS-CoV-2 Nucleocapsid Protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N Protein; novel coronavirus Nucleocapsid Protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N Protein; 2019 ncov N Protein; 2019-nCoV nucleocapsid protein. literatures Specific References (4) | SLM-41413M has been referenced in 4 publications.[IF=14.919] Sonnleitner, Sissy Therese. et al. Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host. NAT COMMUN. 2022 May;13(1):1-12 ELISA ; Human.[IF=4.188] Sissy Therese Sonnleitner. et al. Maintenance of neutralizing antibodies over ten months in convalescent SARS-CoV-2 afflicted patients. 2021 May 07 Human.[IF=4.123] Chunyan Zhang. et al. Foundation and Clinical Evaluation of a New Method for Detecting SARS-CoV-2 Antigen by Fluorescent Microsphere Immunochromatography. Front Cell Infect Mi. 2020; 10: 553837[IF=3.388] Sharma Purva. et al. Pathology of COVID 19 associated acute kidney injury. Clin Kidney J. 2021 Jan;:Immunogen Species Mouse Clonality Monoclonal Clone NO. 6A8 Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 46kDa Form Liquid Concentration ≥1 mg/ml immunogen Recombinant SARS-CoV-2 Nucleocapsid Protein: full length Lsotype IgG1 Purification affinity purified by Protein G Buffer Solution 0.01M PBS(pH7.4) with 0.1% Proclin300 Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
SWISS:
P0DTC9
Gene ID:
43740575
Product Picture Sample:
Lane 1: Recombinant SARS-CoV-2 N Protein(Omicron(B.1.1.529) (P13L,E31del,R32del, S33del,R203K,G204R) at 100ng
Lane 2: Recombinant SARS-CoV-2 N Protein(Omicron(B.1.1.529) (P13L,E31del,R32del, S33del,R203K,G204R) at 50ng
Lane 3: Recombinant SARS-CoV-2 N Protein(Omicron(B.1.1.529) (P13L,E31del,R32del, S33del,R203K,G204R) at 25ng
Lane 4: Recombinant SARS-CoV-2 N Protein(Omicron(B.1.1.529) (P13L,E31del,R32del, S33del,R203K,G204R) at 10ng
Lane 5: Recombinant SARS-CoV-2 N Protein(Omicron(B.1.1.529) (P13L,E31del,R32del, S33del,R203K,G204R) at 5ng
Lane 6: Recombinant SARS-CoV-2 N Protein(WT) at 10ng
Primary: Mouse Anti- SARS-CoV-2 N protein (SLM-41413M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size:45.3 kD
Observed band size:50 kD
Sample:
Lane 1: SARS-CoV-2 N protein(Cat# SL41408P) at 50ng
Lane 2: SARS-CoV-2 N protein(Cat# SL41408P) at 25ng
Lane 3: SARS-CoV-2 N protein(Cat# SL41408P) at 5ng
Lane 4: SARS-CoV-2 N protein(Cat# SL41408P) at 2ng
Lane 5: SARS-CoV-2 N protein(Cat# SL41408P) at 1ng
Lane 6:SARS-CoV-2 N protein(Cat# SL41408P) at 0.5ng
Primary: Anti- SARS-CoV-2 N protein (SL41413M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
Sample:
Lane 1: Recombinant SARS-CoV-2 N protein (WT) (His Tag) (SL41408P)
Lane 2: Recombinant SARS-CoV-2 N protein (Q9H, P67S, P80R, P151L, S183Y) (His Tag) (SL41451P)
Lane 3: Recombinant SARS-CoV-2 N protein (D3L, P13T, D103Y, D128Y, H145Y, R203K, G204R, T205I, S235F) (His Tag) (SL41452P)
Lane 4: Recombinant SARS-CoV-2 N protein (Del204, Del215) (His Tag) (SL41491P)
Lane 5: Recombinant SARS-Cov-2 N protein (R203M, D377Y) (His Tag) (SL41492P)
Lane 6: Recombinant SARS-Cov-2 (Omicron, B.1.1.529) N protein (P13L, E31del, R32del, S33del, R203K, G204R) (N-His Tag) (SL41494P)
Primary: Anti-SARS-CoV-2(2019-nCoV)Nucleocapsid(SLM-41413M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 46 kDa
Observed band size: 52 kDa
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