Product Name	AD7c-NTP
Chinese Name	神经丝蛋白单克隆抗体
Alias	neuronal thread protein AD7c-NTP; AD7c-NTP.
Research Area	Neurobiology  Signal transduction  Apoptosis
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	4E7
React Species	Human,
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	41kDa
Cellular localization	cytoplasmic Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	Recombinant human AD7C NTP full length protein
Lsotype	IgG
Purification	affinity purified by Protein G
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat sequences. However, the mRNA and the encoded protein have been shown to be expressed in neurons, and overexpressed in brains with Alzheimer's disease. In vitro studies also demonstrated that abnormal expression of this gene promoted neuritic sprouting and cell death, associated with dementia in Alzheimer's disease. SWISS: N/A Gene ID: N/A Database links: GenBank: AAC08737 AD7C-NTP是存在于神经元中的一种41Kda的蛋白质，在AD患者脑内选择性升高，和其病理过程相关，AD7C-NTP基因也只在神经元表达，AD患者脑脊液中AD7C-NTP表达升高， AD7C-NTP作为AD早期诊断和确诊的生物化学标志正引起越来越多的关注.

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