Product Name	CD1A
Chinese Name	TlymphocyteCD1A单克隆抗体
Alias	CD 1a; CD1; CD1A Antigen; CD1A antigen, a polypeptide; CD1a molecule; CD1A_HUMAN; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1 alpha 3; epidermal dendritic cell marker CD1a; FCB 6; FCB6; HTA 1; HTA1; hTa1 thymocyte antigen; OTTHUMP00000018907; R 4; R4; T 6; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a; T6.
Research Area	immunology  Cell Surface Molecule  t-lymphocyte
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	11G6
React Species	Human,
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	34kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CD1A
Lsotype	IgG
Purification	affinity purified by Protein G
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] Function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. Subcellular Location: Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts. Tissue Specificity: Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. SWISS: P06126 Gene ID: 909 Database links: Entrez Gene: 909 Human Omim: 188370 Human SwissProt: P06126 Human Unigene: 1309 Human
Product Picture	Sample: Lane 1: Liver (Mouse) Lysate at 40 ug Lane 2: HepG2 (Human) Cell Lysate at 30 ug Lane 3: Thymus (Mouse) Lysate at 40 ug Lane 4: Spinal cord (Mouse) Lysate at 40 ug Primary: Anti-CD1A (SLM-33074M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 34 kD Observed band size: 47 kD

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