Product Name	Methamphetamine(4D2)
Chinese Name	甲基苯丙胺（冰毒）单克隆抗体
Alias	d-Desoxyephedrine hydrochloride; d-N; α-Dimethylphenethylamine hydrochloride; Methylamphetamine hydrochloride; METH.
Product Type	Small molecule anti
Research Area	Drugs and Compounds
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	4D2
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	0.18569kDa
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated Methamphetamine
Lsotype	IgG
Purification	affinity purified by Protein G
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase. 抗甲基安非他明抗体 过量的使用冰毒可导致急性中毒。严重者出现精神混乱、性欲亢进、焦虑、烦躁、幻觉状态。长期滥用可造成慢性中毒、体重下降、消瘦、溃疡、脓肿、指甲脆化和夜间磨牙。静脉注射方式滥用者可引起各种感染合并症；包括肝炎、细菌性心内膜炎、败血症和艾滋病等。

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