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Product Name PAG608 (3E4) Chinese Name 野生型P53诱导基因1单克隆抗体 Alias p53 activated gene 608; PAG608; FLJ12296; MGC10613; OTTHUMP00000211906; OTTHUMP00000211907; p53-activated gene 608 protein; PAG 608; WIG 1; Zinc finger matrin-type protein 3; Zinc finger protein WIG-1; ZMAT3_HUMAN; p53 inducible zinc finger protein; p53 target zinc finger protein; PAG 608; WIG 1; WIG 1/PAG608 protein; WIG1; WIG1/PAG608 protein; Zinc finger matrin type 3; Zinc finger protein WIG 1; Zinc finger protein WIG1; ZMAT 3; ZMAT3. Research Area Tumour Cell biology Chromatin and nuclear signals Signal transduction Apoptosis Cyclin Immunogen Species Mouse Clonality Monoclonal Clone NO. 3E4 React Species Human, Rat, (predicted: Mouse, Chicken, Dog, Pig, Cow, Horse, Guinea Pig, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 32kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human WIG-1/PAG608: 51-150/289 Lsotype IgG1 Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.
Subunit:
Interacts with dsRNA.
Subcellular Location:
Nucleus. Nucleus, nucleolus.
Tissue Specificity:
Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine.
Similarity:
Contains 3 matrin-type zinc fingers.
SWISS:
Q9HA38
Gene ID:
64393
Database links:Entrez Gene: 64393 Human
Entrez Gene: 22401 Mouse
Omim: 606452 Human
SwissProt: Q9HA38 Human
SwissProt: O54836 Mouse
Unigene: 371609 Human
Product Picture Sample:
Cerebrum (Rat) Lysate at 40 ug
Primary: Anti-PAG608 (3E4) (SLM-0957M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 34 kD
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