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Product Name HBZ Chinese Name 血红蛋白ζ链/Hemoglobin ζ 抗体 Alias HBAZ; HBAZ_HUMAN; HBZ 2;HBZ2; Hemoglobin subunit zeta; Hemoglobin zeta; Hemoglobin zeta chain; Zeta globin; Zeta-globin. literatures Specific References (1) | SL9883R has been referenced in 1 publications.[IF=4.105] Tetsuo H et al. Long noncoding RNA CCDC26 as a modulator of transcriptional switching between fetal and embryonic globinsBiochim Biophys Acta Mol Cell Res.2020 Dec 17;1868(3):118931. WB ; Human.Research Area Cardiovascular immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Rat, Dog, Pig, Goose, Chimpanzee, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 16kDa Cellular localization cytoplasmic Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Hemoglobin zeta: 41-140/142 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'. [provided by RefSeq, Nov 2009].
Function:
The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin, synthesized primarily in the yolk sac.
Subunit:
Heterotetramer of two zeta chains and two epsilon chains in early embryonic hemoglobin Gower-1; two zeta chains and two gamma chains in hemoglobin Portland-1.
Tissue Specificity:
Red blood cells.
Similarity:
Belongs to the globin family
SWISS:
P02008
Gene ID:
3050
Database links:Entrez Gene: 3050 Human
Omim: 142310 Human
SwissProt: P02008 Human
Unigene: 585357 Human
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