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Rabbit Anti-Salusin alpha antibody
Rabbit Anti-Salusin alpha antibody
Prosalusin precursor; TOR2A; TORP1; Torsin 2A [Precursor]; Torsin family 2 member A; Torsin related protein 1; TOR2A_HUMAN.
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Details

Product Name Salusin alpha
Chinese Name Cardiovascular调节肽Salusin-α抗体
Alias Prosalusin precursor; TOR2A; TORP1; Torsin 2A [Precursor]; Torsin family 2 member A; Torsin related protein 1; TOR2A_HUMAN.  
Research Area Cardiovascular  immunology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Cow, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 33kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Salusin alpha: 51-150/321 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.

Subcellular Location:
Secreted.

Tissue Specificity:
Isoform 1 is expressed ubiquitously, except in cardiac and endothelial tissues.

Similarity:
Belongs to the clpA/clpB family. Torsin subfamily.

SWISS:
Q5JU69

Gene ID:
27433

Database links:

Entrez Gene: 27433 Human

Omim: 608052 Human

SwissProt: Q5JU69 Human

Unigene: 444106 Human



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