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Product Name MYL7 Chinese Name 肌球蛋白轻链7抗体 Alias atrial isoform; MLC-2a; MLC2a; MLRA_HUMAN; MYL2A; MYL7; Mylc2a; Myosin light chain 2a; Myosin light chain 7 regulatory; Myosin light polypeptide 7 regulatory; Myosin regulatory light chain 2; Myosin regulatory light chain 2 atrial isoform; Myosin regulatory light chain 7. Research Area Cardiovascular Signal transduction Cytoskeleton Extracellular matrix Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Zebrafish, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 19kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MYL7: 101-175/175 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Encoded by the MYL7 gene, myosin regulatory light chain 7, also designated Myosin regulatory light chain 2, atrial isoform (MLC-2a), is part of a hexameric complex of two heavy chains and four light chains predominantly expressed in adult atrial muscle. Myosin regulatory light chain 7 binds calcium and has been shown to be a useful molecular marker for cardiac chamber specification. The co-expression of myosin regulatory light chain 7 and myosin light chain 2 (MLC2v) in the outflow tract and atrioventricular canal, together with the single expression in the atrial (MYL7) and ventricular (MYL2) myo-cardium, permits the delineation of their boundaries. At the amino acid level there is 95% homology between the human and mouse myosin regulatory light chain 7 sequences.
Subunit:
Myosin is an hexamer of 2 heavy chains and 4 light chains.
Tissue Specificity:
Predominantly expressed in adult atrial muscle.
Similarity:
Contains 3 EF-hand domains.
SWISS:
Q01449
Gene ID:
58498
Database links:Entrez Gene: 58498 Human
Omim: 612147 Human
SwissProt: Q01449 Human
Unigene: 75636 Human
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