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Product Name MYOM2 Chinese Name 肌间蛋白2抗体 Alias 165 kDa connectin associated protein; 165 kDa connectin-associated protein; 165 kDa titin associated protein; 165 kDa titin-associated protein; M band protein; M protein; M-protein; MYOM 2; MYOM2; MYOM2_HUMAN; Myomesin (M protein) 2 (165kD); Myomesin (M protein) 2 165kDa; Myomesin (M protein) 2; Myomesin 2; Myomesin family member 2; Myomesin-2; Titin associated protein 165 kD; Titin associated protein; TTNAP. literatures Specific References (1) | SL9864R has been referenced in 1 publications.[IF=1.54] Kim D et al. A Modified Formulation of Sutaehwan Ameliorates Menopausal Anxiety, Depression and Heart Hypertrophy in the VCD-Induced Menopausal Mouse Model. Biol Pharm Bull. 2019;42(9):1471-1481. WB ; Mouse.Research Area Cardiovascular Signal transduction Stem cells Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 165kDa Cellular localization The nucleus cytoplasmic The cell membrane Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MYOM2: 261-360/1465 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Myomesin-1 and myomesin-2 are components of the vertebrate myofibrillar M band and are associated with Titin, Myosin and Connectin. The myomesin proteins are responsible for the formation of a head structure on one end of the Titin string that connects the Z and M bands of the sarcomere. Myomesin-1 and -2 have unique N-terminal domains and are expressed mainly in skeletal muscle.
Function:
Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
Subunit:
Interacts with TTN/titin (By similarity).
Tissue Specificity:
Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
Similarity:
Contains 5 fibronectin type-III domains.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
SWISS:
P54296
Gene ID:
9172
Database links:Entrez Gene: 9172 Human
Entrez Gene: 17930 Mouse
Omim: 603509 Human
SwissProt: P54296 Human
SwissProt: Q14BI5 Mouse
Unigene: 443683 Human
Unigene: 720741 Human
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