Product Name	C1QTNF10
Chinese Name	补体C1q和Tumour坏死因子相关蛋白10抗体
Alias	C1q and tumor necrosis factor related protein 10; C1q domain containing protein; C1QL2; C1QL2_HUMAN; C1QTNF10; Complement C1q-like protein 2; Complement component 1, q subcomponent-like 2; CTRP10; gliacolin like.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	27kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human C1QL2/C1QTNF10: 101-187/187
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	C1qL2, also known as CTRP10 or C1QTNF10, is a 287 amino acid secreted protein that contains one C1q domain and one collagen-like domain. C1qL2 belongs to a large family of multimeric proteins with a signature globular domain homologous to C1QA. These proteins also share structural homology with TNF family members. The gene that encodes C1qL2 consists of approximately 2,653 bases and maps to human chromosome 2q14.2. Consisting of 237 million bases, chromosome 2 encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is due to mutations in the ALMS1 gene. Function: May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Subunit: Forms homotrimers which can further assemble to form higher-order oligomeric complexes (By similarity). Interacts with BAI3 (By similarity). May interact with FAM132B (By similarity). Subcellular Location: Secreted. Similarity: Contains 1 C1q domain. Contains 1 collagen-like domain. SWISS: Q7Z5L3 Gene ID: 165257 Database links: Entrez Gene: 165257 Human Entrez Gene: 226359 Mouse Omim: 614330 Human SwissProt: Q7Z5L3 Human SwissProt: Q8CFR0 Mouse Unigene: 433493 Human Unigene: 337409 Mouse

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