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Product Name C10orf132 Chinese Name 10号染色体开放阅读框132抗体 Alias C10orf133; Chromosome 10 open reading frame 132; GOLGA7B; Golgi autoantigen golgin subfamily a 7B; golgin subfamily A member 7B; MGC131701; Uncharacterized protein C10orf132; GOG7B_HUMAN. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 18kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human C10orf132/GOLGA7B: 61-167/167 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail GOLGA7B , also known as C10orf132 or C10orf133, is a 167 amino acid lipid anchor protein belonging to the Erf4 family. Localizing to Golgi apparatus membrane, GOLGA7B may be involved in the transport of proteins from Golgi to cell surface. The gene encoding GOLGA7B maps to human chromosome 10q24.2 and mouse chromosome 19 C3. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome and Wolman’s syndrome.
Function:
May be involved in protein transport from Golgi to cell surface (By similarity).
Subcellular Location:
Golgi apparatus membrane; Lipid-anchor (By similarity).
Tissue Specificity:
Expressed in brain, but not in lung, nor chondrocytes.
Similarity:
Belongs to the ERF4 family.
SWISS:
Q2TAP0
Gene ID:
401647
Database links:Entrez Gene: 401647 Human
Entrez Gene: 71146 Mouse
SwissProt: Q2TAP0 Human
SwissProt: Q9D428 Mouse
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