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Rabbit Anti-C6orf1/LBH antibody
Rabbit Anti-C6orf1/LBH antibody
C6orf1; CF001_HUMAN; Chromosome 6 open reading frame 1; Hypothetical protein LOC221491; LBH; MGC57858; Protein LBH; Uncharacterized protein C6orf1.
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Details

Product Name C6orf1/LBH
Chinese Name 6号染色体开放阅读框1抗体
Alias C6orf1; CF001_HUMAN; Chromosome 6 open reading frame 1; Hypothetical protein LOC221491; LBH; MGC57858; Protein LBH; Uncharacterized protein C6orf1.  
Research Area Tumour  Cell biology  immunology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 15kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human C6orf1: 1-100/159 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf1 gene product has been provisionally designated C6orf1 pending further characterization.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in spleen, thymus, prostate, testis, uterus, small intestine, colon and peripheral blood leukocytes.

SWISS:
Q5SQH8

Gene ID:
221545

Database links:

Entrez Gene: 221545 Human

SwissProt: Q5SQH8 Human



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