Product Name	PI14
Chinese Name	蛋白酶抑制剂14抗体
Alias	MEPI; Myoepithelium derived serine protease inhibitor; Pancpin; Pancreas specific protein TSA2004; Peptidase inhibitor 14; PI 14; PI14; Protease inhibitor 14; Serine (or cysteine) proteinase inhibitor clade I (neuroserpin) member 2; Serine (or cysteine) proteinase inhibitor clade I (pancpin) member 2; Serpin I2; Serpin peptidase inhibitor clade I (pancpin) member 2; TSA2004; SPI2_HUMAN; SERPINI2.
Research Area	Tumour  Cardiovascular  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	44kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SERPINI2/PI14: 151-250/405
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. Subcellular Location: Secreted Tissue Specificity: Expressed in pancreas and adipose tissues. Similarity: Belongs to the serpin family. SWISS: O75830 Gene ID: 5276 Database links: Entrez Gene: 5276 Human Entrez Gene: 67931 Mouse Entrez Gene: 171149 Rat Omim: 605587 Human SwissProt: O75830 Human SwissProt: Q9JK88 Mouse Unigene: 445555 Human Unigene: 259446 Mouse Unigene: 54500 Rat

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