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Rabbit Anti-JMJD7 antibody
Rabbit Anti-JMJD7 antibody
JmjC domain-containing protein 7; JMJD7; JMJD7_HUMAN; Jumonji domain containing 7; Jumonji domain-containing protein 7.
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  • NO.:SL9486R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
  • Goods click count:24
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Details

Product Name JMJD7
Chinese Name 组蛋白去甲基转移酶JMJD7抗体
Alias JmjC domain-containing protein 7; JMJD7; JMJD7_HUMAN; Jumonji domain containing 7; Jumonji domain-containing protein 7.  
Research Area Cell biology  immunology  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 36kDa
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human JMJD7: 221-316/316 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail A crucial regulator of chromatin dynamics and DNA transcription is the covalent modification and methylation of histones. Generally, methylation of certain lysine residues on Histone H3 and Histone H4 can be associated with transcriptionally active or inactive chromatin. This regulation has profound effects on the expression of genes and is part of an epigenetic memory network that determines cell fate. JMJD7 (Jumonji domain-containing protein 7) is a member of a family of JMJC domain-containing histone demethylases that are directly involved in removing methyl residues from distinct and unique lysine residues. These actions are implicated in gene expression and the regulation of cell senescence. JMJC domain-containing histone demethylases are also likely involved in development via their ability to regulate gene expression. JMJD7 contains one JMJC domain and was originally thought to be an alternatively spliced isoform of PLA2G4B.

Similarity:
Contains 1 JmjC domain.

SWISS:
P0C870

Gene ID:
100137047

Database links:

Entrez Gene: 100137047 Human

Entrez Gene: 433466 Mouse

Entrez Gene: 100137086 Rat

SwissProt: P0C870 Human

SwissProt: P0C872 Mouse

Unigene: 198161 Human

Unigene: 482417 Mouse



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