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Product Name SRFBP1 Chinese Name 血清应答因子Binding protein1抗体 Alias p49 / STRAP; p49; p49/STRAP; serum response factor binding protein 1; Serum response factor-binding protein 1; SRF dependent transcription regulation associated protein; SRF-dependent transcription regulation-associated protein; SRFBP 1; SRFBP1. Research Area Cardiovascular transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 49kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SRFBP1: 51-150/429 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.
Function:
May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells (By similarity).
Subunit:
Interacts with SRF. Forms complexes with SRF and SRF cofactors ARID2, MYOCD and NKX2-5. Interacts with the N-terminus of SLC2A4 (By similarity).
Subcellular Location:
Cytoplasm.perinuclear region.
Tissue Specificity:
Abundantly expressed in heart and skeletal muscle, and at much lower levels in brain and lung.
SWISS:
Q8NEF9
Gene ID:
153443
Database links:Entrez Gene: 153443 Human
Entrez Gene: 67222 Mouse
Omim: 610479 Human
SwissProt: Q8NEF9 Human
SwissProt: Q9CZ91 Mouse
Unigene: 107622 Human
Unigene: 100617 Mouse
Unigene: 101802 Rat
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