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Rabbit Anti-TSPAN3 antibody
Rabbit Anti-TSPAN3 antibody
tetraspanin 3; tetraspanin TM4 A; TM4 A; TM4A; TM4SF8; transmembrane 4 superfamily member 8; TSPAN 3; TSPAN-3; TSPAN3; TSN3_HUMAN.
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  • NO.:SL9412R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep,)
    Applications:WB ELISA
    concentration:1mg/ml
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Details

Product Name TSPAN3
Chinese Name 四分子交联体3/四旋蛋白3/四次Transmembrane protein3抗体
Alias tetraspanin 3; tetraspanin TM4 A; TM4 A; TM4A; TM4SF8; transmembrane 4 superfamily member 8; TSPAN 3; TSPAN-3; TSPAN3; TSN3_HUMAN.  
Research Area Cell biology  immunology  Signal transduction  Cell differentiation  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 28kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human TSPAN3: 61-160/253 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail TSPAN3 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Two alternative transcripts encoding different isoforms have been described.

Function:
Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.

Subunit:
Interacts with claudin-11/CLDN11 and integrins.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the tetraspanin (TM4SF) family.

SWISS:
O60637

Gene ID:
10099

Database links:

Entrez Gene: 10099 Human

Entrez Gene: 56434 Mouse

Omim: 613134 Human

SwissProt: Q3SZR9 Cow

SwissProt: O60637 Human

SwissProt: Q9QY33 Mouse



Product Picture
Sample:
spinal cord(mouse) Lysate at 40 ug
Primary: Anti- TSPAN3 (SL9412R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 28kD
Observed band size: 28 kD

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