Product Name	BCL7B
Chinese Name	BCL7B蛋白抗体
Alias	B cell CLL/lymphoma 7 protein family member B; B cell CLL/lymphoma 7B; BCL 7B; BCL7B_HUMAN.
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	22kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human BCL7B: 1-100/202
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	BCL7B shows high homology to the BCL7A protein, which is known to be directly involved in a complex chromosomal translocation in Burkitt lymphoma cell lines. The specific function of BCL7B has not yet been determined. However, it may play a role in lung tumor development or progression. The BCL7B gene is located at a chromosomal region commonly deleted in the congenital disorder, Williams syndrome. Function: May play a role in lung tumor development or progression. Tissue Specificity: Ubiquitous. DISEASE: Note=BCL7B is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of BCL7B may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. Similarity: Belongs to the BCL7 family. SWISS: Q9BQE9 Gene ID: 9275 Database links: Entrez Gene: 9275 Human Entrez Gene: 12054 Mouse Omim: 605846 Human SwissProt: Q9BQE9 Human SwissProt: Q921K9 Mouse Unigene: 647051 Human Unigene: 405834 Mouse

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