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Product Name SLC43A2 Chinese Name 溶质载体蛋白家族43成员2抗体 Alias FLJ23848; L-type amino acid transporter 4; Large neutral amino acids transporter small subunit 4; LAT4; LAT4_HUMAN; MGC34680; SLC43A2; Solute carrier family 43 (amino acid system L transporter) member 2; Solute carrier family 43 member 2. Research Area Cell biology Signal transduction The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 62kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC43A2: 81-180/569 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail System L amino acid transporters, such as SLC43A2, mediate sodium-independent transport of bulky neutral amino acids across cell membranes (Bodoy et al., 2005 [PubMed 15659399]).[supplied by OMIM, Mar 2008]
Function:
Sodium-, chloride, pH-independent high affinity transport of large neutral amino acids.
Subcellular Location:
Membrane.
Tissue Specificity:
Detected in several tissues with, higher expression in placenta, kidney and peripheral blood leukocytes. In the kidney is detected in epithelial cells of the distal tubule and collecting duct. In the intestine is expressed mainly in crypt cells of the intestinal microvilli ans epithelial cells in the base of the villus.
Post-translational modifications:
Glycosylated.
Similarity:
Belongs to the SLC43A transporter (TC 2.A.1.44) family.
SWISS:
Q8N370
Gene ID:
124935
Database links:
Entrez Gene: 100072377 Horse
Entrez Gene: 124935 Human
Entrez Gene: 100342229 Rabbit
Omim: 610791 Human
SwissProt: Q8N370 Human
Unigene: 160550 Human
Unigene: 204988 Rat
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