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Product Name GDPD5 Chinese Name 甘油磷酸二酯酶磷酸结构域5抗体 Alias GDE2; Gdpd5; GDPD5_HUMAN; Glycerophosphodiester phosphodiesterase 2; Glycerophosphodiester phosphodiesterase domain containing 5; Glycerophosphodiester phosphodiesterase domain-containing protein 5; PP1665. Research Area Cell biology immunology Neurobiology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Cow, Horse, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 69kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GDPD5: 301-400/605 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.
Function:
Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.
Subunit:
Interacts with PRDX1; forms a mixed-disulfide with PRDX1, leading to disrupt intramolecular disulfide bond between Cys-25 and Cys-571 (By similarity).
Subcellular Location:
Endomembrane system. Cytoplasm; perinuclear region. Cell projection; growth cone. In a punctate perinuclear pattern.
Post-translational modifications:
Intramolecular disulfide bond between Cys-25 and Cys-571 is reduced by PRDX1 (By similarity).
Similarity:
Belongs to the glycerophosphoryl diester phosphodiesterase family.
Contains 1 GDPD domain.
SWISS:
Q8WTR4
Gene ID:
81544
Database links:Entrez Gene: 81544 Human
Entrez Gene: 233552 Mouse
Omim: 609632 Human
SwissProt: Q8WTR4 Human
SwissProt: Q640M6 Mouse
Unigene: 503297 Human
Unigene: 286317 Mouse
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