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Rabbit Anti-GDPD5 antibody
Rabbit Anti-GDPD5 antibody
GDE2; Gdpd5; GDPD5_HUMAN; Glycerophosphodiester phosphodiesterase 2; Glycerophosphodiester phosphodiesterase domain containing 5; Glycerophosphodiester phosphodiesterase domain-containing protein 5; PP1665.
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  • NO.:SL9207R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,(predicted: Mouse,Rat,Dog,Cow,Horse,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name GDPD5
Chinese Name 甘油磷酸二酯酶磷酸结构域5抗体
Alias GDE2; Gdpd5; GDPD5_HUMAN; Glycerophosphodiester phosphodiesterase 2; Glycerophosphodiester phosphodiesterase domain containing 5; Glycerophosphodiester phosphodiesterase domain-containing protein 5; PP1665.  
Research Area Cell biology  immunology  Neurobiology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Dog, Cow, Horse, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 69kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GDPD5: 301-400/605 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.

Function:
Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.

Subunit:
Interacts with PRDX1; forms a mixed-disulfide with PRDX1, leading to disrupt intramolecular disulfide bond between Cys-25 and Cys-571 (By similarity).

Subcellular Location:
Endomembrane system. Cytoplasm; perinuclear region. Cell projection; growth cone. In a punctate perinuclear pattern.

Post-translational modifications:
Intramolecular disulfide bond between Cys-25 and Cys-571 is reduced by PRDX1 (By similarity).

Similarity:
Belongs to the glycerophosphoryl diester phosphodiesterase family.
Contains 1 GDPD domain.

SWISS:
Q8WTR4

Gene ID:
81544

Database links:

Entrez Gene: 81544 Human

Entrez Gene: 233552 Mouse

Entrez Gene: 100627912 Pig

Entrez Gene: 499211 Rat

Omim: 609632 Human

SwissProt: Q8WTR4 Human

SwissProt: Q640M6 Mouse

Unigene: 503297 Human

Unigene: 286317 Mouse



Product Picture
Sample:
Hela(Human) Cell Lysate at 30 ug
A549(Human) Cell Lysate at 30 ug
Primary: Anti- GDPD5 (SL9207R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size:52 kD

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