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Product Name IGSF9 Chinese Name 免疫球蛋白超家族成员9抗体 Alias IGSF9A; Dasm1; Dendrite arborization and synapse maturation protein 1; IGSF9 immunoglobulin superfamily, member 9; Immunoglobulin superfamily member 9A; immunoglobulin superfamily, member 9; Ncaml; Nrt1; Protein turtle homolog A; TUTLA_HUMAN. Research Area Cell biology Neurobiology Cell Surface Molecule Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, ) Applications ELISA=1:5000-10000 Flow-Cyt=1μg /Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 124kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IGSF9: 551-680/1179 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF9 (immunoglobulin superfamily, member 9), also known as Nrt1 or IGSF9A, is a 1,179 amino acid single-pass type I membrane protein expressed in a wide variety of fetal tissues at eight and fourteen weeks of gestation. Belonging to the immunoglobulin superfamily and the Turtle family, IGSF9 is thought to play a role in dendrite outgrowth and synapse maturation. IGSF9 contains two fibronectin type-III domains and five Ig-like (immunoglobulin-like) domains. IGSF9 interacts with MAGI-2 and Shank 1, both of which contain SH3 (Src-homology 3) domains. Protein-protein interactions are central events in cellular signal transduction and are often mediated by SH3 domains. IGSF9 is encoded by a gene located on human chromosome 1q23.2 and mouse chromosome 1 H3.
Function:
Functions in dendrite outgrowth and synapse maturation (By similarity).
Subunit:
Interacts with MAGI2 and SHANK1.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Similarity:
Belongs to the immunoglobulin superfamily. Turtle family.
Contains 2 fibronectin type-III domains.
Contains 5 Ig-like (immunoglobulin-like) domains.
SWISS:
Q9P2J2
Gene ID:
57549
Database links:
Entrez Gene: 57549 Human
Entrez Gene: 93842 Mouse
Omim: 609738 Human
SwissProt: Q9P2J2 Human
SwissProt: Q05BQ1 Mouse
Unigene: 591472 Human
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