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Rabbit Anti-HN1 antibody
Rabbit Anti-HN1 antibody
Androgen regulated protein 2; Androgen-regulated protein 2; ARM2; Hematological and neurological expressed 1; Hematological and neurological expressed 1 protein; HN1; HN1_HUMAN; HN1A.
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  • NO.:SL9069R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Rabbit,)
    Applications:ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name HN1
Chinese Name 雄激素调节蛋白2抗体
Alias Androgen regulated protein 2; Androgen-regulated protein 2; ARM2; Hematological and neurological expressed 1; Hematological and neurological expressed 1 protein; HN1; HN1_HUMAN; HN1A.  
Research Area Cell biology  immunology  Kinases and Phosphatases  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Rabbit, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 16kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human HN1/ARM2: 21-100/154 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Hematological and neurological expressed 1 protein (HN1) is a 154 amino acid member of the HN1 family. HN1 has been proposed to play a role in embryo development, specifically hemopoietic cell and neurological development. Localized to the nucleus, HN1 is expressed in many fetal and adult tissues, with highest levels of expression in brain, colon, prostate, testis, thymus, skeletal muscle, peripheral blood cells and placenta. HN1 has been identified to have processed pseudogenes in the mouse, rat and human genomes, suggesting that HN1 and its pseudogenes represent a novel gene family. Three isoforms of HN1 exist as a result of alternative splicing events. HN1L (hematological and neurological expressed 1-like protein), also known as C16orf34 or L11, is a 190 amino acid protein that belongs to the HN1 family. Localizing to the cytoplasm as well as the nucleus, HN1L is expressed in liver, kidney, prostate, testis and uterus. HN1L gets upregulated in certain carcinomas, including squamous cell carcinoma (SCC), adenocarcinoma (AC), adenosquamous cell carcinoma (ASCC) and bronchioalveolar carcinoma (BAC), and is also expressed in breast and uterine tumors. HN1L, along with HN1, may be involved in embryo development.

Subcellular Location:
Nucleus

Tissue Specificity:
Expressed in testis, skeletal muscle, thymus, prostate, colon, peripheral blood cells, brain and placenta.

Post-translational modifications:
Isoform 3 initiator methionine is either acetylated or removed. In the latter case, the new N-terminal amino acid is then N-acetylated.

Similarity:
Belongs to the HN1 family.

SWISS:
Q9UK76

Gene ID:
51155

Database links:

Entrez Gene: 51155 Human

Entrez Gene: 15374 Mouse

Entrez Gene: 287828 Rat

SwissProt: Q9UK76 Human

SwissProt: P97825 Mouse

SwissProt: Q6AXU6 Rat

Unigene: 532803 Human

Unigene: 1775 Mouse

Unigene: 198910 Rat



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