Product Name	PDZD8
Chinese Name	PDZ结构域PDZK8蛋白抗体
Alias	PDZ domain containing 8; PDZ domain containing protein 8; PDZD 8; PDZK 8; PDZK8; Sarcoma antigen NY SAR 104; Sarcoma antigen NY SAR 84; Sarcoma antigen NY SAR 84/NY SAR 104; bA129M16.2; FLJ25412; FLJ34427; OTTHUMP00000046868; PDZD8_HUMAN.
literatures	Specific References  (1)     |     SL9043R has been referenced in 1 publications. [IF=5.924] Yudai Hojo. et al. Sunitinib and Pterostilbene Combination Treatment Exerts Antitumor Effects in Gastric Cancer via Suppression of PDZD8. INT J MOL SCI. Int J Mol Sci. 2022 Jan;23(7):4002  WB,IHC,IP ;  Human,Mouse.   PubMed:35409367
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, Dog, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	128kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PDZD8: 901-1000/1154
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	PDZD8 contains a PDZ domain. PDZ domains are protein-interaction domains that are often found in multi-domain scaffolding proteins. The function of this protein remains unknown. Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. May inhibit herpes simplex virus 1 infection at an early stage. May promote retroviral infection. Subunit: Interacts with MSN. Interacts with HIV-1 Gag polyprotein p55. Similarity: Contains 1 PDZ (DHR) domain. Contains 1 phorbol-ester/DAG-type zinc finger. SWISS: Q8NEN9 Gene ID: 118987 Database links: Entrez Gene: 118987 Human SwissProt: Q8NEN9 Human Unigene: 501149 Human
Product Picture	Sample: Panc-1(Human) Cell Lysate at 30 ug Primary: Anti-PDZD8 (SL9043R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 128 kD Observed band size: 130kD Sample: Hela(Human) Cell Lysate at 30 ug Primary: Anti-PDZD8 (SL9043R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 128 kD Observed band size: 130 kD Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PDZD8 Polyclonal Antibody, Unconjugated (SL9043R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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