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Product Name EFHA1 Chinese Name EFHA1蛋白抗体 Alias EF-HA1; EF hand domain containing family member A1; EF hand domain family A1; EF hand domain family member A1; EFHA1 EF hand domain family member A1; FLJ25016; FLJ34588; Smhs2 homolog; 1110008L20Rik; EFHA1_HUMAN. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 50kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human EFHA1: 351-434/434 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. EF-HA1 (EF-hand domain family, member A1) is a 434 amino acid protein that contains four EF-hand domains, suggesting a role in calcium-mediated events throughout the cell. The gene encoding EF-HA1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Similarity:
Contains 4 EF-hand domains.
SWISS:
Q8IYU8
Gene ID:
221154
Database links:Entrez Gene: 221154 Human
Entrez Gene: 68514 Mouse
Omim: 610632 Human
SwissProt: Q8IYU8 Human
SwissProt: Q8CD10 Mouse
Unigene: 412103 Human
Unigene: 26834 Mouse
Unigene: 64644 Rat
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