Product Name	SCY1 like 3
Chinese Name	SCY1样蛋白3抗体
Alias	Ezrin binding protein PACE 1; Ezrin-binding protein PACE-1; PACE 1; PACE1; PACE1_HUMAN; Protein associating with the carboxyl terminal domain of ezrin; Protein-associating with the carboxyl-terminal domain of ezrin; SCY1 like 3 (S. cerevisiae); SCY1 like 3; SCY1 like protein 3; SCY1-like protein 3; SCYL 3; SCYL3.
Research Area	Cell biology  immunology  Cell adhesion molecule
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	82kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SCY1 like 3: 1-100/742
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012] Function: May play a role in regulating cell adhesion/migration complexes in migrating cells. Subcellular Location: Cytoplasm. Golgi apparatus. Cell projection > lamellipodium. Colocalized with EZR/VIL2, actin and CD44 in lamellipodia. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: May be myristoylated; myristoylation may target it to Golgi compartment. Phosphorylated. Similarity: Belongs to the protein kinase superfamily. Contains 4 HEAT repeats. Contains 1 protein kinase domain. SWISS: Q8IZE3 Gene ID: 57147 Database links: Entrez Gene: 57147 Human Omim: 608192 Human SwissProt: Q8IZE3 Human Unigene: 435560 Human

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