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Product Name NUDT9 Chinese Name ADP核糖磷酸水解酶9抗体 Alias Adenosine diphosphoribose pyrophosphatase; ADP ribose diphosphatase; ADP ribose phosphohydrolase; ADP ribose pyrophosphatase, mitochondrial precursor; ADP ribose pyrosphosphatase NUDT9; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADP-ribose pyrophosphatase, mitochondrial; ADPR PPase; ADPR-PPase; EC 3.6.1.13; Nucleoside diphosphate linked moiety X motif 9; Nucleoside diphosphate linked moiety X type motif 9; Nucleoside diphosphate-linked moiety X motif 9; Nudix (nucleoside diphosphate linked moiety X) type motif 9; Nudix motif 9; NUDT10; NUDT9; NUDT9_HUMAN. Research Area Tumour Cell biology Neurobiology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Horse, Rabbit, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 40kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NUDT9: 101-200/350 Lsotype IgG Purification affinity purified by Protein A Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Function:
Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate.
Subcellular Location:
Mitochondrion.
Tissue Specificity:
Ubiquitously expressed but isoform 1 is the most predominant isoform.
Similarity:
Belongs to the Nudix hydrolase family. NudF subfamily.
Contains 1 nudix hydrolase domain.
SWISS:
Q9BW91
Gene ID:
53343
Database links:Entrez Gene: 53343 Human
Entrez Gene: 74167 Mouse
Omim: 606022 Human
SwissProt: Q9BW91 Human
SwissProt: Q8BVU5 Mouse
Unigene: 149500 Human
Unigene: 241484 Mouse
Unigene: 22103 Rat
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